It may also irritate the upper airway and cause some coughing. M. Balali-Mood, ... L. Etemad, in Encyclopedia of Toxicology (Third Edition), 2014. Fanning may provide some additional relief. Clinical effects of oleoresin capsicum (pepper spray) on the human cornea and conjunctiva. Many agencies have authorized, or are authorizing, the use of OC sprays by their officers and have found that OC sprays are more effective and safer than either CN or CS gases. If this ingredient is ingested … The effects range bum tearing, involuntary closing of the eyes, and burning and redness of ex- posed skin, to coughing, gagging, and shortness of breath; to loss of motor skills or muscle coordiiation. Slit lamp examination may be required to remove any corneal or conjunctival particulate matter. G.D. Dukes, ... G.J. Exposure to lacrimators causes immediate pain, blepharospasm, lacrimation, rhinorrhea, coughing, and sneezing, but usually no permanent tissue damage (Grant and Schuman, 1993; Blain, 2003). Similarly, skin contact can result in burning, irrigation, and erythema. Ophthalmology 2000;107:2186-9. Ophthalmic effects involve blepharospasm, conjunctivitis, peri-orbital oedema, and corneal pathology. CS also has a high flammability rating and has caused some structure fires. Extracted from chili peppers, oleoresin capsicum is the active component of pepper spray. Oleoresin Capsicum (CAP-STUN) Toxicity from Aerosol Exposure William A Watson, Katrina R Stremel, and Ellen J Westdorp Annals of Pharmacotherapy 2016 30 : 7-8 , 733-735 JA. With higher ocular concentrations, chemical burns with keratitis and loss of the corneal epithelium may occur (Hoffman, 1967). Capsaicin affects thin sensory neurons, nonsensory neurons, and nonneural excitable cells. These agents include 1-chloroacetphenone (CN), o-chlorobenzylidene malononitrile (CS), and Oleoresin capsicum (OC). In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Exposure of the airway and respiratory tract may cause coughing, gagging, and shortness of breath. It produces nausea, vomiting, diarrhea, abdominal cramping, and other systemic effects (including headache and depression), in addition to the mucosal irritation characteristic of the other riot-control agents. This salt may also be used for purposes not listed in this medication guide. Side effects of capsicum oleoresin may include redness and irritation at the site of application. Ophthalmology 2000;107:2186-9. Inadequate decontamination may result in secondary exposure cases. By continuing you agree to the use of cookies. The final oleoresin contains several branched-chain alkyl vanillylamides, in addition to capsaicin, the major component in OC. Side Effects: Precautions: Missed Dose: Drug Interactions: capsicum Oleoresin Capsaicin, Trixaicin, Capzasin-P, Recapsin, Arthritis Pain Relief, Capsaicin Apr, Medi-Gen, Zostrix, Theragen, Arthritis Formula Capsaicin, Caprex Uses Capsicum Oleoresin is used on the skin to relieve pain in conditions such as arthritis, shingles, psoriasis or diabetic neuropathy. CS and CN are effective because when released, they are dispersed as a microscopic powder, which acts as a ‘powdered barb’. Capsicum annuum. (n.d.). Oleoresin Capsicum (OC) spray is the generic term for the extract of naturally occurring peppers of the capsicum family. Acute ventilatory complaints have been reported, including the case series of nine marines who were exposed to CS during strenuous exercise and developed cough, shortness of breath, and hemoptysis and hypoxia in several of those exposed. No teratogenicity or carcinogenicity has been demonstrated in humans or animals (Folb and Talmud, 1989; Blain, 2003). The active ingredient in pepper spray is capsaicin, which is a chemical derived from plants in the Capsicum genus, including chillies. Abstract. The agent may remain active on surfaces or clothing. 1 Pepper spray causes irritation and inflammation, and produces a range of signs and symptoms affecting the eyes, mouth, throat, lungs, and skin. Rethink MS Treatment; SPF and Your Skin Type; AFib-Related Strokes; Enlarged Prostate Facts ; … Preparation made from the oleoresin in cayenne and oleoresin's isolated constituent 'Capsaicin' is used as topical analgesic in OTC (over the counter) market. IDENTIFICATION Product Description: CAPSICUM OLEORESIN HIGH PUNGENCY CAS # 8023-77-6 FEMA Number 2234 Other means of identification Vigon Item # 501219 Concentrated aromatic and flavor ingredient which may be used in … Cornea 2011;30:1042-4. Treatment is supportive. An increased incidence of gastrointestinal cancer has been reported in human populations who routinely include peppers in their diet. 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